When working with an external monitor attached to laptop I find I often lose my cursor briefly (that is, it's still there, I just don't know where I've put it - I think it's a sign I'm getting old). Part of the problem is that I tend to use keyboard shortcuts a lot and so often just stop paying attention to the cursor. Thanks to Youpi Key keyboard shortcuts are now also the solution: in it I've defined a universal short-cut (control-option-k) that bumps the cursor to the centre of my main screen. Pretty damned handy. Discuss