For what it's worth, I've been using Mozilla 1.0RC1 for OS X, instead of MSIE, for a few days now, and subjectively it seems snappier. I had a lot of problems with Mozilla 0.9.9, none of which seem to be happening with one-point-oh.
I'm not on the Well any more, but I seem to recall that Our Cory posted a magisterial rant about OS X email-program options over there a few months ago. I'm sufficiently annoyed with Eudora, and unsure of its future, that I'd like to prod him into doing another such overview. (Of course, yes, running all kinds of fine Unix character-based email clients is trivial on OS X, and in fact I have mutt working, but I want to know my click on the bunny options.)